Uncomplicated Urinary Tract Infection — NEJM
Uncomplicated Urinary Tract Infection — NEJM
Clinical Practice. Uncomplicated Urinary Tract Infection. Thomas M. Hooton, M.D. N Engl J Med 2012; 366:1028-1037 March 15, 2012 DOI: 10.1056/NEJMcp1104429

Limiting protein is still sometimes used in cats with advanced kidney failure, but it has been my professional experience that helps these cats much more than protein restriction. Additionally, "Dry cat foods with their high plant content, cause a very alkaline urine pH…This unnaturally high concentration of minerals and other constituents in the urine along with alkaline pH, leads to UTI (Urinary Tract Inflammation). Indirect dipstick tests are informative, but less sensitive, than microscopic examination of the urine. During that time period, allergies, urinary problems, digestive problems and kidney disease in cats have all increased. Much of the time, the exact cause is unknown, and a number of things may be contributing to impaired kidney function, including diet.

Also, the low magnesium content in diets designed to decrease urinary stone and crystal formation may adversely affect the kidneys over time. However, it has been estimated that at least one-third of all women in the United States are diagnosed with a UTI by the time they reach 24 years of age. Since so much kidney function is lost by the time disease is usually detected, we need to do everything we can to help our cats maintain good kidney health in the first place. Should you do it? Recent research demonstrates that diets high in protein have no detrimental effect on the kidneys, and animals with mildly decreased kidney function do not benefit from reduced protein diets. Any abnormality of the urinary tract that interferes with the drainage of urine (e.

Many diseases of the urinary tract produce significant pyuria without bacteriuria, including staghorn calculi, tuberculosis, and infections caused by spp. Basic chemistry tells us that the more concentrated a solution is, and in this case the solution is urine, the more likely any are to precipitate out and form crystals and stones. Dry cat food has only been around for about the past 70 years. Raw diets, which contain adequate moisture as well as appropriate amounts of protein and fat, can also help cats get back to a more natural urinary balance of and urine concentration. Water is drawn into the kidneys and makes the cat urinate more. Dietary Protein Levels Affect Water Intake and Urinary Excretion of Magnesium and Phosphorous in Laboratory Cats  16. The UTI incidence ratio in middle-aged women to men is 30:1; yet, during later decades of life, the ratio of infection in women to men with bacteriuria progressively decreases. It is important that cats receive good quality protein in appropriate amounts without excessive levels of phosphorous to help maintain kidney function. Cooper, " Protein and Calorie Effects on Progression of Induced Chronic Renal Failure in Cats  4. A study of the urine of 198 feral cats eating a natural, raw diet found no evidence of urinary stones in any of the cats.



Acute Uncomplicated Urinary Tract Infections
Acute Uncomplicated Urinary Tract Infections Online Medical Reference - from definition and diagnosis through risk factors, treatments and prevention. Co-authored by ... Can a urinary tract infection cause brown discharge Feeding for Urinary and Kidney Health - Feline Nutrition ...There is a connection between what cats are fed and disease. Diet plays a role in disease syndromes such as kidney disease and urinary problems.

Among young healthy women with cystitis, the infection recurs in 25% of women within 6 months after the first episode. UTI is differentiated from asymptomatic bacterial colonization by the presence of an inflammatory response, and the associated signs and symptoms that result from bacterial invasion. You may be familiar with the names of these by-products of protein breakdown if your cat has had blood work done. Postmenopausal women also may be at increased risk for UTI given their increased prevalence of cystocele and elevated volumes of post-void residual urine. Cooked egg whites are high in protein and very low in phosphorus.

Additionally, "Dry cat foods with their high plant content, cause a very alkaline urine pH…This unnaturally high concentration of minerals and other constituents in the urine along with alkaline pH, leads to UTI (Urinary Tract Inflammation). You may think that the cat can make it up by drinking more water, but cats innately have a low thirst drive, as they evolved to eat prey consisting of so much moisture. Much of the time, the exact cause is unknown, and a number of things may be contributing to impaired kidney function, including diet. This indicates that 70 to 80% of the cat's natural instinctive diet should consist of water. One factor may be that a woman's urethra is short, allowing bacteria quick access to the bladder.

Phosphorous limitation can be accomplished through the substitution of cooked egg whites for a portion of the meat in the diet, which dilutes the overall amount of phosphorus in the serving. Cats fed a dry diet exclusively are at a significant water deficit compared to cats eating a natural diet. Nevertheless, acute uncomplicated UTI can occur in men, especially in those with risk factors like insertive anal intercourse or lack of circumcision. Preventing dental disease can be an important factor in the long-term health of your cat's kidneys. Anaerobic microorganisms are frequently encountered in suppurative infections of the genitourinary tract (e. Pyuria is defined as the presence of at least 10 leukocytes/mm of un-centrifuged urine, or more than 5 to 10 leukocytes/high-power field in centrifuged urine. Feline urine tends to be more concentrated than urine of other mammalian species. UTI in men conventionally have been considered complicated because most infections occur in infants or in the elderly in association with urologic abnormalities. Bacterial urinary infections usually spread to the urinary tract through an ascending route of fecal flora, from the fecal reservoir through the urethra into the bladder, particularly in patients with intermittent or indwelling catheters. Physical examination, including a pelvic examination, should be carried out in women with lower urinary tract symptoms (LUTS) to exclude gynecologic, neurologic, or colorectal disorders.


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